This animated children's film takes place in The House of Mouse, where Mickey Mouse is hosting a show. Various villainous characters from almost every mentionable Disney classic are featured as guests at the show along with many other lovable favorites. The trouble starts as the villains plan to take over the show as to play nothing but film clips featuring themselves. It's up to Mickey Mouse and his closest cohorts to save the House of Mouse from the evil characters before it's too late.